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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1LB All Species: 24.85
Human Site: S372 Identified Species: 36.44
UniProt: Q86YB8 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YB8 NP_063944.3 467 53543 S372 G D K K G A K S L K E E F R L
Chimpanzee Pan troglodytes XP_001156276 467 53719 S372 G D K K G A K S L K E E F R L
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 K373 G D K K E A H K L K E D F R L
Dog Lupus familis XP_546074 753 83528 S658 G D K K G A K S L K E E F R L
Cat Felis silvestris
Mouse Mus musculus Q8R2E9 467 53500 S372 G D K K G A K S L K E E F R L
Rat Rattus norvegicus Q8R4A1 464 54000 K369 G D K N E A H K L K E D F R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512742 679 76557 S584 G E K K G A K S L K E E F R L
Chicken Gallus gallus XP_419554 467 53247 S372 G D K K G A K S L K E E F R L
Frog Xenopus laevis Q6DD71 465 53720 K371 G D K K E A A K L K E D F R Q
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 K364 G N N K E A M K L K E D F K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 H387 I A S I K F K H D Y K E K F R
Honey Bee Apis mellifera XP_623933 471 55049 D380 S E A Q L L K D Q F K Q H F R
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 A366 G V E S H A R A L R E E F R S
Sea Urchin Strong. purpuratus XP_796844 897 101920 Q797 G D Q Q Q A L Q L R E E F R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 L369 Q F R N I S A L M D C V G C E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 S395 F K N G E G P S L K E D F R N
Conservation
Percent
Protein Identity: 100 98.5 60 60.2 N.A. 94 59.3 N.A. 63.3 87.5 58.6 52.5 N.A. 46.1 49 40.7 25.8
Protein Similarity: 100 98.9 75 61.3 N.A. 96.5 74.5 N.A. 66.7 92.7 74.9 68 N.A. 63.9 65.8 59.2 35.9
P-Site Identity: 100 100 73.3 100 N.A. 100 66.6 N.A. 93.3 100 66.6 53.3 N.A. 13.3 6.6 46.6 53.3
P-Site Similarity: 100 100 80 100 N.A. 100 73.3 N.A. 100 100 73.3 73.3 N.A. 20 33.3 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 38.8 N.A. 28.5
Protein Similarity: N.A. N.A. N.A. 57.3 N.A. 39.6
P-Site Identity: N.A. N.A. N.A. 0 N.A. 40
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 75 13 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % C
% Asp: 0 57 0 0 0 0 0 7 7 7 0 32 0 0 0 % D
% Glu: 0 13 7 0 32 0 0 0 0 0 82 57 0 0 7 % E
% Phe: 7 7 0 0 0 7 0 0 0 7 0 0 82 13 0 % F
% Gly: 75 0 0 7 38 7 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 7 0 13 7 0 0 0 0 7 0 0 % H
% Ile: 7 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 57 57 7 0 50 25 0 69 13 0 7 7 0 % K
% Leu: 0 0 0 0 7 7 7 7 82 0 0 0 0 0 57 % L
% Met: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 13 13 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 7 13 7 0 0 7 7 0 0 7 0 0 7 % Q
% Arg: 0 0 7 0 0 0 7 0 0 13 0 0 0 75 13 % R
% Ser: 7 0 7 7 0 7 0 44 0 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _